产品介绍9/div>
产品说明
一般描?/p>
CD21 (also known as complement receptor 2 (CR2), C3d receptor, or EBV receptor) is a 140 kDa membrane protein on B-lymphocytes to which the Epstein-Barr virus (EBV) binds during infection of these cells. The antigen is absent on T-lymphocytes, monocytes, and granulocytes.
Anti-CD21 is useful in the identification of follicular dendritic cell matrix found in normal lymph node and tonsillar tissue. This antibody also labels follicular dendritic cell sarcomas. Anti-CD21 is valuable in differentiating follicular lymphoma with marginal zone differentiation from marginal zone lymphoma with follicular involvement. It also plays a role in distinguishing among nodular lymphocyte predominant Hodgkin lymphoma, lymphocyte-rich classic Hodgkin lymphoma, and T-cell/histiocyte-rich B-cell lymphoma in combination with other B-cell and T-cell markers.Anti-CD21 is also useful in identifying abnormal follicular dendritic cell pattern in angioimmunoblastic T-cell lymphoma and follicular T-cell lymphoma.
联系
CD21 Positive Control Slides, Product No. 121S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).
外形
Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide
其他说明
For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com
法律信息
Cell Marque is a trademark of sigma-aldrich Co. LLC
基本信息
产品性质
| 质量水平 |
500 100 |
| 生物来源 |
mouse |
| 偶联?/td> |
unconjugated |
| 抗体形式 |
culture supernatant |
| antibody product type |
primary antibodies |
| 克隆 |
2G9, monoclonal |
| 描述 |
For In Vitro Diagnostic Use in Select Regions (See Chart) |
| 形式 |
buffered aqueous solution |
| species reactivity |
human |
| 包装 |
vial of 0.1 mL concentrate (121M-14) vial of 0.5 mL concentrate (121M-15) bottle of 1.0 mL predilute (121M-17) vial of 1.0 mL concentrate (121M-16) bottle of 7.0 mL predilute (121M-18) |
| manufacturer/tradename |
Cell Marque? |
| technique(s) |
immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:25-1:100 |
| 同位?亚型 |
IgG2a |
| 控制 |
tonsil |
| 运输 |
wet ice |
| 储存温度 |
2-8ℂ/td> |
| 可视匕/td> |
membranous |