产品介绍９/div>
产品说明
一般描?/p>
Thyroid-stimulating hormone (also known as TSH or thyrotropin) is a peptide hormone synthesized and secreted by thyrotrope cells in the anterior pituitary gland which regulate the endocrine function of the thyroid gland. TSH is a glycoprotein and consists of two subunits, the alpha and the beta subunit, which are non-covalently bound to one another. The alpha subunit of TSH is also present in two other pituitary glycoprotein hormones: Follicle stimulating hormone and luteinizing hormone and, in primates, in the placental hormone chorionic gonadotropin. Each of these hormones also has a unique beta subunit, which provides receptor specificity. In other words, TSH is composed of alpha subunit bound to the TSH beta subunit, and TSH associates only with its own receptor. Free alpha and beta subunits have essentially no biological activity. Anti-TSH reacts with TSH-producing cells (thyrotrophs), and is a useful marker in classification of pituitary tumors and the differential identification of primary and metastatic tumors in the pituitary gland.1-5
质量
联系
TSH Positive Control Slides, Product No. 211S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).
外形
Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide.
制备说明
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其他说明
For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com
法律信息
Cell Marque is a trademark of sigma-aldrich Co. LLC
基本信息
产品性质
| 生物来源 |
rabbit |
| 质量水平 |
500
100 |
| 偶联?/td> |
unconjugated |
| 抗体形式 |
culture supernatant |
| antibody product type |
primary antibodies |
| 克隆 |
EP254, monoclonal |
| 描述 |
(For In Vitro Diagnostic Use in Select Regions (See Chart)) |
| 形式 |
buffered aqueous solution |
| species reactivity |
human |
| 包装 |
bottle of 1.0 mL predilute (211R-17)
bottle of 7.0 mL predilute (211R-18)
vial of 0.1 mL concentrate (211R-14)
vial of 0.5 mL concentrate (211R-15)
vial of 1.0 mL concentrate (211R-16) |
| manufacturer/tradename |
Cell Marque? |
| technique(s) |
immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:100-1:500 |
| 同位?亚型 |
IgG |
| 运输 |
wet ice |
| 储存温度 |
2-8ℂ/td> |
安全信息
| 储存分类代码 |
12 - Non Combustible Liquids |
| WGK |
WGK 2 |
| 闪点(F) |
Not applicable |
| 闪点(C) |
Not applicable |
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