产品介绍９/div>
产品说明
一般描?/p>
Monocarboxylate Transporter 1 (MCT1), also known as Solute carrier family 16 member 1 (SLC16A1), catalyzes the rapid transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, branched-chain oxo acids derived from leucine, valine and isoleucine, and the ketone bodies acetoacetate, beta-hydroxybutyrate and acetate. Monocarboxylate Transporter 1 is located in the cell membrane, and is widely expressed in both normal and cancer cells. Monocarboxylate Transporter 1 is involved in symptomatic deficiency in lactate transport (SDLT).
特异?/p>
This antibody recognizes the C-terminus of Monocarboxylate Transporter 1.
免疫厞/p>
KLH-conjugated linear peptide corresponding to the C-terminus of rat Monocarboxylate Transporter 1.
Epitope: C-terminus
应用
Immunohistochemistry Analysis: A 1:2,500 dilution from a representative lot detected rat skeletal muscle and rat renal cortex tissues.
Anti-Monocarboxylate Transporter 1 Antibody is a highly specific chicken polyclonal antibody, that targets MCT1 & has been tested in western blotting & IHC (Paraffin).
Research Sub Category
Signaling Neuroscience
Research Category
Neuroscience
质量
Evaluated by Western Blot in rat brain membrane tissue lysate.
Western Blotting Analysis: 0.5 ?g/mL of this antibody detected rat brain membrane tissue lysate in 10 ?g of rat brain membrane tissue lysate.
目标描述
Bands are observed at ~44 kDa and ~55 kDa This protein has been observed at ~47 kDa (Sepponen, K., et al. (2003). Acta Physiol Scand. 177(1):79-86.). In addition this protein has been observed at ~55 kDa in certain cell lysates, except in the rumen where two distinct bands appear at ~47 kDa and ~55 kDa (Koho, N., et al. (2005). Comp Biochem Physiol A Mol Integr Physiol. 141(1):29-34.). It is also known to be glycosylated (Carpenter, L., et al. (1996). Biochim Biophys Acta. 1279(2):157-163).
联系
Replaces: AB1286
外形
Affinity purified
Purified chicken polyclonal IgY in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
储存及稳定?/p>
Stable for 1 year at 2-8C from date of receipt.
分析说明
Control
Rat brain membrane tissue lysate
其他说明
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
| eCl@ss |
32160702 |
| NACRES |
NA.41 |
产品性质
| 生物来源 |
chicken |
| 质量水平 |
100 |
| 抗体形式 |
affinity purified immunoglobulin |
| antibody product type |
primary antibodies |
| 克隆 |
polyclonal |
| 纯化方式 |
affinity chromatography |
| species reactivity |
rat |
| species reactivity (predicted by homology) |
mouse (immunogen homology) |
| technique(s) |
immunohistochemistry: suitable (paraffin)
western blot: suitable |
| 同位?亚型 |
IgY |
| NCBI登记叶/td> |
NP_036848 |
| UniProt登记叶/td> |
P53987 |
| 运输 |
wet ice |
安全信息
| 储存分类代码 |
12 - Non Combustible Liquids |
| WGK |
WGK 1 |
| 闪点(F) |
Not applicable |
| 闪点(C) |
Not applicable |
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