双{[((异丙氧基羰基)氧基]甲基}（{[((2R)-1-(6-氨基-9H-嘌呤-9-�?-2-丙烷基]氧基}甲基)膦酸� 富马酸酯

产品名称９�/div>

202138-50-9
Tenofovir disoproxil fumarate
Bis{[(Isopropoxycarbonyl)oxy]methyl} ({[(2R)-1-(6-amino-9H-purin-9-yl)-2-propanyl]oxy}methyl)phosphonate fumarate
Bis(POC)PMPA fumarate
富马酸替诺福韦二吡呋�?br />替诺福韦� 富马酸酯
双{[((异丙氧基羰基)氧基]甲基}（{[((2R)-1-(6-氨基-9H-嘌呤-9-�?-2-丙烷基]氧基}甲基)膦酸� 富马酸酯
Bis(POC)PMPA 富马酸酯

产品介绍９�/div>

产品说明

一般描�?/p>

Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards

生化/生理作用

富马酸替诺福韦酯是替诺福韦的一种前药，一种可引起DNA转录提前终止的核苷酸类似物逆转录酶抑制�?nRTI)。在T细胞系和原代血淋巴细胞中，替诺福韦酯的抗病毒活性是替诺福韦�?00倍以上，原因就在于其快速的细胞间摄取。富马酸替诺福韦酯在HIV/AIDS和慢性乙肝病毒感染的预防和治疗中已被单独和经多种联合使用，并位于国际卫生组织的基本药品清单中、�/p>

分析说明

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

其他说明

This Certified Reference Material (CRM) is produced and certified in accordance withISO 17034andISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

附注

To see an example of a Certificate of Analysis for this material enter LRAB2763 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.

基本信息

经验(实验)分子弎�/td>	C₁₉H₃₀N₅O₁₀P �� C₄H₄O₄
分子野�/td>	635.51
MDL编号	MFCD08141829
NACRES	NA.24

产品性质

质量水平	300
等级	certified reference material pharmaceutical secondary standard
CofA	current certificate can be downloaded
包装	pkg of 500 mg
application(s)	pharmaceutical
格式	neat
药典可追溯�?/td>	traceable to USP 1643656
储存温度	2-8ℂ�/td>
SMILES string	OC(/C=C/C(O)=O)=O.NC1=C2C(N(C[C@@H](C)OCP(OCOC(OC(C)C)=O)(OCOC(OC(C)C)=O)=O)C=N2)=NC=N1
InChI	1S/C19H30N5O10P.C4H4O4/c1-12(2)33-18(25)28-9-31-35(27,32-10-29-19(26)34-13(3)4)11-30-14(5)6-24-8-23-15-16(20)21-7-22-17(15)24;5-3(6)1-2-4(7)8/h7-8,12-14H,6,9-11H2,1-5H3,(H2,20,21,22);1-2H,(H,5,6)(H,7,8)/b;2-1+/t14-;/m1./s1
InChI key	VCMJCVGFSROFHV-WZGZYPNHSA-N