产品名称９/div>
32911-62-9
Withanolide A
Withaniol
(5α,6α,7α,22
R)-6,7-Epoxy-5,20,22-trihydroxy-1-oxo-ergosta-2,24-dien-26-oic acid δ-lactone
产品介绍９/div>
产品说明
一般描?/p>
Withanolide A is classified under the steroidal lactone group of bioactive compounds that are majorly found inWithania somnifera(L.).
应用
Refer to the products Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Withanolide A may be used as an analytical standard for the determination of withanolide A in:
- Mentat tablet, an Indian herbal medicine by UHPLC coupled to tandem mass spectrometry (MS/MS) operating with ESI, along with multivariate analysis.
- Withania somniferaby ultra-high performance liquid chromatography-hybrid triple quadrupole linear ion trap mass spectrometer (UHPLC-QqQ LIT-MS) equipped with electrospray ionization (ESI) source and MRM detection, along with multivariate analysis as well as HPLC combined with diode array detector (DAD).
- Withania coagulansby LC-QqQ-ESI-MS/MS.
生化/生理作用
C28-steroidal lactone that can induce nerve development and improve nervous system function. Potential therapeutic for neurologic disorders like Alzheimer′s and Parkinson′s disease. In primary rat cortical neurons, withanolide A significantly up-regulated IDE levels, a prominent enzyme involved in degrading amyloid protein, which may help to clear excess amyloid protein from an Alzheimers-inflicted brain.
包装
Bottomless glass bottle. Contents are inside inserted fused cone.
基本信息
| 经验(实验)分子弎/td> |
C28H38O6 |
| 分子野/td> |
470.60 |
| MDL编号 |
MFCD07779143 |
| PubChem化学物质编号 |
329765849 |
| NACRES |
NA.24 |
产品性质
| 等级 |
analytical standard |
| 质量水平 |
100 |
| 测定 |
95.0% (HPLC) |
| 保质朞/td> |
limited shelf life, expiry date on the label |
| technique(s) |
HPLC: suitable
gas chromatography (GC): suitable |
| application(s) |
food and beverages |
| 格式 |
neat |
| SMILES string |
CC1=C(C)C(=O)O[C@H](C1)[C@](C)(O)[C@H]2CC[C@H]3[C@H]4[C@H](CC[C@]23C)[C@@]5(C)C(=O)C=CC[C@]5(O)[C@H]6O[C@@H]46 |
| InChI |
1S/C28H38O6/c1-14-13-20(33-24(30)15(14)2)27(5,31)18-9-8-16-21-17(10-12-25(16,18)3)26(4)19(29)7-6-11-28(26,32)23-22(21)34-23/h6-7,16-18,20-23,31-32H,8-13H2,1-5H3/t16-,17-,18-,20+,21-,22-,23-,25-,26-,27+,28-/m0/s1 |
| InChI key |
DXWHOKCXBGLTMQ-SFQAJKIESA-N |
安全信息
| 储存分类代码 |
13 - Non Combustible Solids |
| WGK |
WGK 3 |
| 闪点(F) |
Not applicable |
| 闪点(C) |
Not applicable |
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