产品名称9/div>
1346683-42-8
3-[[3,5-Bis(trifluoromethyl)phenyl]amino]-4-[[(1S,2S)-2-(1-pyrrolidinyl)cyclohexyl]amino]-3-cyclobutene-1,2-dione
3-[[3,5-?三氟甲基)苯基]氨基]-4-[(1S,2S)-2-(1-吡咯烷基)环己基]氨基]-3-环丁?1,2-二酮
产品介绍9/div>
Technical Notes:
1.Mannich Reaction: The asymmetric addition of the present HWE reagents to N-ca rbamoyl imines
generated in situ was achieved. The corresponding Mannich adducts can be further transformed to aza- MBH type products in good to excellent enantioselectivities.
References:
1. Chem. Sci., 2011, 2, 1918-1921.