Monoclonal Anti-HERPUD1 antibody produced in mouse

Monoclonal Anti-HERPUD1 antibody produced in mouse
Mif1
HERP
KIAA0025
SUP

产品介绍９�/div>

产品说明

一般描�?/p>

The accumulation of unfolded proteins in the endoplasmic reticulum (ER) triggers the ER stress response. This response includes the inhibition of translation to prevent further accumulation of unfolded proteins, the increased expression of proteins involved in polypeptide folding, known as the unfolded protein response (UPR), and the destruction of misfolded proteins by the ER-associated protein degradation (ERAD) system. This gene may play a role in both UPR and ERAD. Its expression is induced by UPR and it has an ER stress response element in its promoter region while the encoded protein has an N-terminal ubiquitin-like domain which may interact with the ERAD system. This protein has been shown to interact with presenilin proteins and to increase the level of amyloid-beta protein following its overexpression. Alternative splicing of this gene produces multiple transcript variants, some encoding different isoforms. The full-length nature of all transcript variants has not been determined. (provided by RefSeq)

免疫厞�/p>

HERPUD1 (AAH00086, 1 a.a. ~ 391 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Sequence
MESETEPEPVTLLVKSPNQRHRDLELSGDRGWSVGHLKAHLSRVYPERPRPEDQRLIYSGKLLLDHQCLRDLLPKQEKRHVLHLVCNVKSPSKMPEINAKVAESTEEPAGSNRGQYPEDSSSDGLRQREVLRNLSSPGWENISRPEAAQQAFQGLGPGFSGYTPYGWLQLSWFQQIYARQYYMQYLAATAASGAFVPPPSAQEIPVVSAPAPAPIHNQFPAENQPANQNAAPQVVVNPGANQNLRMNAQGGPIVEEDDEINRDWLDWTYSAATFSVFLSILYFYSSLSRFLMVMGATVVMYLHHVGWFPFRPRPVQNFPNDGPPPDVVNQDPNNNLQEGTDPETEDPNHLPPDRDVLDGEQTSPSFMSTAWLVFKTFFASLLPEGPPAIAN

外形

Solution in phosphate buffered saline, pH 7.4

基本信息

NACRES

NA.41

产品性质

生物来源	mouse
偶联�?/td>	unconjugated
抗体形式	purified immunoglobulin
antibody product type	primary antibodies
克隆	3E10, monoclonal
形式	buffered aqueous solution
分子野�/td>	antigen ~69.12 kDa
species reactivity	human
technique(s)	capture ELISA: suitable indirect ELISA: suitable western blot: 1-5 ��g/mL
同位�?亚型	IgG1��
NCBI登记叶�/td>	BC000086
UniProt登记叶�/td>	Q15011
运输	dry ice
储存温度	?20ℂ�/td>
Gene Information	human ... HERPUD1(9709)

安全信息

储存分类代码	13 - Non Combustible Solids
WGK	WGK 1
闪点(F)	Not applicable
闪点(C)	Not applicable