产品介绍９/div>
产品说明
一般描?/p>
Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding the mu class of enzymes are organized in a gene cluster on chromosome 1p13.3 and are known to be highly polymorphic. These genetic variations can change an individuals susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs. Diversification of these genes has occurred in regions encoding substrate-binding domains, as well as in tissue expression patterns, to accommodate an increasing number of foreign compounds. Multiple transcript variants, each encoding a distinct protein isoform, have been identified. (provided by RefSeq)
免疫厞/p>
GSTM4 (AAH15513.1, 23 a.a. ~ 119 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
YTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLPYLIDGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQAMDVSNQLARVCYSPD
外形
Solution in phosphate buffered saline, pH 7.4
基本信息
产品性质
| 生物来源 |
mouse |
| 偶联?/td> |
unconjugated |
| 抗体形式 |
purified immunoglobulin |
| antibody product type |
primary antibodies |
| 克隆 |
4B4, monoclonal |
| 形式 |
buffered aqueous solution |
| species reactivity |
human |
| technique(s) |
indirect ELISA: suitable
western blot: 1-5 g/mL |
| 同位?亚型 |
IgG2a |
| UniProt登记叶/td> |
Q03013 |
| 运输 |
dry ice |
| 储存温度 |
?20ℂ/td> |
| Gene Information |
human ... GSTM4(2948) |
安全信息
| 储存分类代码 |
12 - Non Combustible Liquids |
| 闪点(F) |
Not applicable |
| 闪点(C) |
Not applicable |
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