Monoclonal Anti-GRN, (C-terminal) antibody produced in mouse

Monoclonal Anti-GRN, (C-terminal) antibody produced in mouse
GP88
GEP
PEPI
PGRN
PCDGF

产品介绍９�/div>

产品说明

一般描�?/p>

Granulins are a family of secreted, glycosylated peptides that are cleaved from a single precursor protein with 7.5 repeats of a highly conserved 12-cysteine granulin/epithelin motif. The 88 kDa precursor protein, progranulin, is also called proepithelin and PC cell-derived growth factor. Cleavage of the signal peptide produces mature granulin which can be further cleaved into a variety of active, 6 kDa peptides. These smaller cleavage products are named granulin A, granulin B, granulin C, etc. Epithelins 1 and 2 are synonymous with granulins A and B, respectively. Both the peptides and intact granulin protein regulate cell growth. However, different members of the granulin protein family may act as inhibitors, stimulators, or have dual actions on cell growth. Granulin family members are important in normal development, wound healing, and tumorigenesis. (provided by RefSeq)

免疫厞�/p>

GRN (NP_002078, 494 a.a. ~ 593 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Sequence
SCEKEVVSAQPATFLARSPHVAVKDVECGEGHFCHDNQTCCRDNRQGWACCPYRQGVCCADRRHCCPAGFRCAARGTKCLRREAPRWDAPLRDPALRQLL

外形

Solution in phosphate buffered saline, pH 7.4

基本信息

NACRES

NA.41

产品性质

生物来源	mouse
偶联�?/td>	unconjugated
抗体形式	purified immunoglobulin
antibody product type	primary antibodies
克隆	1A8, monoclonal
形式	buffered aqueous solution
分子野�/td>	antigen ~37.11 kDa
species reactivity	human
technique(s)	capture ELISA: suitable indirect ELISA: suitable
同位�?亚型	IgG2a��
NCBI登记叶�/td>	NM_002087
UniProt登记叶�/td>	P28799
运输	dry ice
储存温度	?20ℂ�/td>
Gene Information	human ... GRN(2896)

安全信息

储存分类代码	13 - Non Combustible Solids
WGK	WGK 1
闪点(F)	Not applicable
闪点(C)	Not applicable