产品名称9/div>
Monoclonal Anti-GRM7 antibody produced in mouse
MGLUR7
GLUR7
mGlu7
GPRC1G
FLJ40498
产品介绍9/div>
产品说明
一般描?/p>
L-glutamate is the major excitatory neurotransmitter in the central nervous system, and it activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors that have been divided into three groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5, and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3, while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities. Multiple transcript variants encoding different isoforms have been found for this gene. (provided by RefSeq)
免疫厞/p>
GRM7 (NP_000835, 431 a.a. ~ 520 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
ADYRGVCPEMEQAGGKKLLKYIRNVNFNGSAGTPVMFNKNGDAPGRYDIFQYQTTNTSNPGYRLIGQWTDELQLNIEDMQWGKGVREIPA
外形
Clear solution
基本信息
产品性质
| 生物来源 |
mouse |
| 偶联?/td> |
unconjugated |
| 抗体形式 |
ascites fluid |
| antibody product type |
primary antibodies |
| 克隆 |
1H5, monoclonal |
| 分子野/td> |
antigen ~36.01 kDa |
| species reactivity |
human |
| technique(s) |
indirect ELISA: suitable western blot: 1:500-1:1000 |
| 同位?亚型 |
IgG |
| NCBI登记叶/td> |
NM_000844 |
| UniProt登记叶/td> |
Q14831 |
| 运输 |
dry ice |
| 储存温度 |
?20ℂ/td> |
| Gene Information |
human ... GRM7(2917) |
安全信息
| 储存分类代码 |
13 - Non Combustible Solids |
| WGK |
WGK 1 |
| 闪点(F) |
Not applicable |
| 闪点(C) |
Not applicable |