产品介绍９/div>
产品说明
一般描?/p>
This gene encodes an enzyme that catalyzes the production of geranyl pyrophosphate and farnesyl pyrophosphate from isopentenyl pyrophosphate and dimethylallyl pyrophosphate. The resulting product, farnesyl pyrophosphate, is a key intermediate in cholesterol and sterol biosynthesis, a substrate for protein farnesylation and geranylgeranylation, and a ligand or agonist for certain hormone receptors and growth receptors. Drugs that inhibit this enzyme prevent the post-translational modifications of small GTPases and have been used to treat diseases related to bone resorption. Multiple pseudogenes have been found on chromosomes 1, 7, 14, 15, 21 and X. Multiple transcript variants encoding different isoforms have been found for this gene
免疫厞/p>
FDPS (NP_001995.1, 320 a.a. ~ 419 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
VTGKIGTDIQDNKCSWLVVQCLQRATPEQYQILKENYGQKEAEKVARVKALYEELDLPAVFLQYEEDSYSHIMALIEQYAAPLPPAVFLGLARKIYKRRK
特点和优劾/p>
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
外形
Solution in phosphate buffered saline, pH 7.4
基本信息
产品性质
| 质量水平 |
100 |
| 生物来源 |
mouse |
| 偶联?/td> |
unconjugated |
| 抗体形式 |
purified immunoglobulin |
| antibody product type |
primary antibodies |
| 克隆 |
3A6, monoclonal |
| 形式 |
buffered aqueous solution |
| species reactivity |
human |
| technique(s) |
capture ELISA: suitable |
| 同位?亚型 |
IgG2a |
| NCBI登记叶/td> |
NM_002004 |
| UniProt登记叶/td> |
P14324 |
| 运输 |
dry ice |
| 储存温度 |
?20ℂ/td> |
| Gene Information |
human ... FDPS(2224) |
安全信息
| 储存分类代码 |
12 - Non Combustible Liquids |
| 闪点(F) |
Not applicable |
| 闪点(C) |
Not applicable |
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