Monoclonal Anti-FBXO32 antibody produced in mouse

Monoclonal Anti-FBXO32 antibody produced in mouse
FLJ32424
MAFbx
Fbx32
MGC33610

产品介绍９�/div>

产品说明

一般描�?/p>

This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class and contains an F-box domain. This protein is highly expressed during muscle atrophy, whereas mice deficient in this gene were found to be resistant to atrophy. This protein is thus a potential drug target for the treatment of muscle atrophy. Alternative splicing of this gene results in two transcript variants encoding two isoforms of different sizes. (provided by RefSeq)

免疫厞�/p>

FBXO32 (AAH24030.1, 1 a.a. ~ 210 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Sequence
MNILEKVVLKVLEDQQNIRLIRELLQTLYTSLCTLVQRVGKSVLVGNINMWVYRMETILHWQQQLNNIQITRPAFKGLTFTDLPLCLQLNIMQRLSDGRDLVSLGQAAPDLHVLSEDRLLWKKLCQYHFSERQIRKRLILSGKGQLDWKKMYFKLVRCYPRKEQYGDTLQLRKHCHILSWKGTDHPCTANNPESCSVSLSPQDFINLFKF

外形

Solution in phosphate buffered saline, pH 7.4

基本信息

NACRES

NA.41

产品性质

质量水平	100
生物来源	mouse
偶联�?/td>	unconjugated
抗体形式	purified immunoglobulin
antibody product type	primary antibodies
克隆	1D6, monoclonal
形式	buffered aqueous solution
分子野�/td>	antigen ~49.21 kDa
species reactivity	human
technique(s)	indirect ELISA: suitable
同位�?亚型	IgG2a��
NCBI登记叶�/td>	BC024030
UniProt登记叶�/td>	Q969P5
运输	dry ice
储存温度	?20ℂ�/td>
Gene Information	human ... FBXO32(114907)

安全信息

储存分类代码	13 - Non Combustible Solids
WGK	WGK 1
闪点(F)	Not applicable
闪点(C)	Not applicable