Monoclonal Anti-FADD, (C-terminal) antibody produced in mouse

Monoclonal Anti-FADD, (C-terminal) antibody produced in mouse
MGC8528
MORT1
GIG3

产品介绍９�/div>

产品说明

一般描�?/p>

The protein encoded by this gene is an adaptor molecule that interacts with various cell surface receptors and mediates cell apoptotic signals. Through its C-terminal death domain, this protein can be recruited by TNFRSF6/Fas-receptor, tumor necrosis factor receptor, TNFRSF25, and TNFSF10/TRAIL-receptor, and thus it participates in the death signaling initiated by these receptors. Interaction of this protein with the receptors unmasks the N-terminal effector domain of this protein, which allows it to recruit caspase-8, and thereby activate the cysteine protease cascade. Knockout studies in mice also suggest the importance of this protein in early T cell development. (provided by RefSeq)

免疫厞�/p>

FADD (AAH00334, 109 a.a. ~ 208 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Sequence
GKDWRRLARQLKVSDTKIDSIEDRYPRNLTERVRESLRIWKNTEKENATVAHLVGALRSCQMNLVADLVQEVQQARDLQNRSGAMSPMSWNSDASTSEAS

外形

Solution in phosphate buffered saline, pH 7.4

基本信息

NACRES

NA.41

产品性质

质量水平	100
生物来源	mouse
偶联�?/td>	unconjugated
抗体形式	purified immunoglobulin
antibody product type	primary antibodies
克隆	3C3, monoclonal
形式	buffered aqueous solution
分子野�/td>	antigen ~37 kDa
species reactivity	human
technique(s)	capture ELISA: suitable indirect ELISA: suitable western blot: 1-5 ��g/mL
同位�?亚型	IgG1��
NCBI登记叶�/td>	BC000334
UniProt登记叶�/td>	Q13158
运输	dry ice
储存温度	?20ℂ�/td>
Gene Information	human ... FADD(8772)

安全信息

储存分类代码	13 - Non Combustible Solids
WGK	WGK 1
闪点(F)	Not applicable
闪点(C)	Not applicable