Monoclonal Anti-EXOSC1 antibody produced in mouse

Monoclonal Anti-EXOSC1 antibody produced in mouse
CGI-108
Csl4p
hCsl4p
CSL4
p13
SKI4
Ski4p

产品介绍９�/div>

产品说明

一般描�?/p>

This gene encodes a core component of the exosome. The mammalian exosome is required for rapid degradation of AU rich element-containing RNAs but not for poly(A) shortening. The association of this protein with the exosome is mediated by protein-protein interactions with ribosomal RNA-processing protein 42 and ribosomal RNA-processing protein 46. (provided by RefSeq)

免疫厞�/p>

EXOSC1 (AAH22067, 1 a.a. ~ 195 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Sequence
MAPPVRYCIPGERLCNLEEGSPGSGTYTRHGYIFSSLAGCLMKSSENGALPVVSVVRETESQLLPDVGAIVTCKVSSINSRFAKVHILYVGSMPLKNSFRGTIRKEDVRATEKDKVEIYKSFRPGDIVLAKVISLGDAQSNYLLTTAENELGVVVAHSESGIQMVPISWCEMQCPKTHTKEFRKVARVQPEFLQT

生化/生理作用

The exosome complex facilitates the splicing and degradation of mRNAs and non-coding RNAs. It is also essential for epigenetic gene regulation. It endogenously suppresses erythroid maturation. Within the complex, Exosc1 (exosome component 1) associates with Exosc6 to stabilize the complex. The binding of Exosc10 to Exosc1, Exosc6, and Exosc8 enhances the activity of the complex and positions Exosc1 for RNA binding.

外形

Solution in phosphate buffered saline, pH 7.4

基本信息

NACRES

NA.41

产品性质

质量水平	100
生物来源	mouse
偶联�?/td>	unconjugated
抗体形式	purified immunoglobulin
antibody product type	primary antibodies
克隆	2E9, monoclonal
形式	buffered aqueous solution
分子野�/td>	antigen ~47.56 kDa
species reactivity	human
technique(s)	capture ELISA: suitable immunofluorescence: suitable indirect ELISA: suitable western blot: 1-5 ��g/mL
同位�?亚型	IgG2b��
NCBI登记叶�/td>	BC022067
UniProt登记叶�/td>	Q9Y3B2
运输	dry ice
储存温度	?20ℂ�/td>
Gene Information	human ... EXOSC1(51013)

安全信息

储存分类代码	13 - Non Combustible Solids
WGK	WGK 1
闪点(F)	Not applicable
闪点(C)	Not applicable