Monoclonal Anti-EXOC7, (C-terminal) antibody produced in mouse

Monoclonal Anti-EXOC7, (C-terminal) antibody produced in mouse
DKFZp686J04253
EX070
FLJ46415
EXOC1
FLJ40965
Exo70p
YJL085W
EXO70
2-5-3p

产品介绍９�/div>

产品说明

一般描�?/p>

EXOC7 is a component of the exocyst, which is an evolutionarily conserved octameric protein complex essential for exocytosis. The exocyst targets secretory vesicles at specific domains of the plasma membrane for cell surface expansion and protein secretion (Zuo et al., 2006 [PubMed 17086175]).[supplied by OMIM

免疫厞�/p>

EXOC7 (NP_001013861, 586 a.a. ~ 684 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Sequence
VFQPGVKLRDKERQIIKERFKGFNDGLEELCKIQKAWAIPDTEQRDRIRQAQKTIVKETYGAFLQKFGSVPFTKNPEKYIKYGVEQVGDMIDRLFDTSA

应用

Monoclonal Anti-EXOC7, (C-terminal) antibody produced in mouse is suitable for indirect ELISA and western blot assays.

生化/生理作用

EXOC7 (Exocyst complex component 7) is mainly involved in the exocytosis, a membrane trafficking process of intracellular protein elements such as hormones and neurotransmitters, membrane proteins and lipids to specific domains of the plasma membrane. Exocytosis plays a vital role in the cellular growth, development and cell polarity establishment. During exocytosis, it directly connects with the plasma membrane through its direct interaction with phosphatidylinositol 4,5-bisphosphate (PI(4,5)P(2)). It has also been reported that the interaction between EXOC7 and PI(4,5)P(2) is highly essential for the docking and fusion of post-Golgi secretory vesicles.

外形

Solution in phosphate buffered saline, pH 7.4

基本信息

NACRES

NA.41

产品性质

质量水平	100
生物来源	mouse
偶联�?/td>	unconjugated
抗体形式	purified immunoglobulin
antibody product type	primary antibodies
克隆	1B7, monoclonal
形式	buffered aqueous solution
分子野�/td>	antigen ~37 kDa
species reactivity	human
technique(s)	indirect ELISA: suitable western blot: 1-5 ��g/mL
同位�?亚型	IgG2a��
NCBI登记叶�/td>	NM_001013839
UniProt登记叶�/td>	Q9UPT5
运输	dry ice
储存温度	?20ℂ�/td>
Gene Information	human ... EXOC7(23265)

安全信息

储存分类代码	13 - Non Combustible Solids
WGK	WGK 1
闪点(F)	Not applicable
闪点(C)	Not applicable