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Monoclonal Anti-ENSA antibody produced in mouse

品牌
Sigma-Aldrich
货号
SAB1403775
规格纯度
clone 1H7, purified immunoglobulin, buffered aqueous solution
参考价栻/div>
5045.46 兂/span>*本价格含增值税贸/span>
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数量
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产品名称9/div>
Monoclonal Anti-ENSA antibody produced in mouse
MGC8394
MGC4319
MGC78563
产品介绍9/div>

产品说明

一般描?/p>

The protein encoded by this gene belongs to a highly conserved cAMP-regulated phosphoprotein (ARPP) family. This protein was identified as an endogenous ligand for the sulfonylurea receptor, ABCC8/SUR1. ABCC8 is the regulatory subunit of the ATP-sensitive potassium (KATP) channel, which is located on the plasma membrane of pancreatic beta cells and plays a key role in the control of insulin release from pancreatic beta cells. This protein is thought to be an endogenous regulator of KATP channels. In vitro studies have demonstrated that this protein modulates insulin secretion through the interaction with KATP channel, and this gene has been proposed as a candidate gene for type 2 diabetes. At least eight alternatively spliced transcript variants encoding distinct isoforms have been observed. (provided by RefSeq)

免疫厞/p>

ENSA (AAH00436, 1 a.a. ~ 121 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Sequence
MSQKQEEENPAEETGEEKQDTQEKEGILPERAEEAKLKAKYPSLGQKPGGSDFLMKRLQKGQKYFDSGDYNMAKAKMKNKQLPSAGPDKNLVTGDHIPTPQDLPQRKSSLVTSKLAGGQVE

外形

Solution in phosphate buffered saline, pH 7.4

基本信息

NACRES NA.41

产品性质

质量水平 100
生物来源 mouse
偶联?/td> unconjugated
抗体形式 purified immunoglobulin
antibody product type primary antibodies
克隆 1H7, monoclonal
形式 buffered aqueous solution
分子野/td> antigen ~39.42 kDa
species reactivity human
technique(s) capture ELISA: suitable
indirect ELISA: suitable
western blot: 1-5 g/mL
同位?亚型 IgG2b
NCBI登记叶/td> BC000436
UniProt登记叶/td> O43768
运输 dry ice
储存温度 ?20ℂ/td>
Gene Information human ... ENSA(2029)

安全信息

储存分类代码 13 - Non Combustible Solids
WGK WGK 1
闪点(F) Not applicable
闪点(C) Not applicable

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