Monoclonal Anti-ENC1 antibody produced in mouse

Monoclonal Anti-ENC1 antibody produced in mouse
CCL28
TP53I10
NRPB
FLJ39259
KLHL37
PIG10
KLHL35
ENC-1

产品介绍９�/div>

产品说明

一般描�?/p>

DNA damage and/or hyperproliferative signals activate wildtype p53 tumor suppressor protein (TP53; MIM 191170), inducing cell cycle arrest or apoptosis. Mutations that inactivate p53 occur in 50% of all tumors. Polyak et al. (1997) [PubMed 9305847] used serial analysis of gene expression (SAGE) to evaluate cellular mRNA levels in a colorectal cancer cell line transfected with p53. Of 7,202 transcripts identified, only 14 were expressed at levels more than 10-fold higher in p53-expressing cells than in control cells. Polyak et al. (1997) [PubMed 9305847] termed these genes ��p53-induced genes,�� or PIGs, several of which were predicted to encode redox-controlling proteins. They noted that reactive oxygen species (ROS) are potent inducers of apoptosis. Flow cytometric analysis showed that p53 expression induces ROS production, which increases as apoptosis progresses under some conditions. The authors stated that the PIG10 gene, also called ENC1, encodes an actin-binding protein.[supplied by OMIM

免疫厞�/p>

ENC1 (NP_003624, 17 a.a. ~ 98 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Sequence
SINIYLFHKSSYADSVLTHLNLLRQQRLFTDVLLHAGNRTFPCHRAVLAACSRYFEAMFSGGLKESQDSEVNFDNSIHPEVL

外形

Solution in phosphate buffered saline, pH 7.4

基本信息

NACRES

NA.41

产品性质

质量水平	100
生物来源	mouse
偶联�?/td>	unconjugated
抗体形式	purified immunoglobulin
antibody product type	primary antibodies
克隆	3C10, monoclonal
形式	buffered aqueous solution
分子野�/td>	antigen ~35.13 kDa
species reactivity	human
technique(s)	indirect ELISA: suitable western blot: 1-5 ��g/mL
同位�?亚型	IgG1��
NCBI登记叶�/td>	NM_003633
UniProt登记叶�/td>	O14682
运输	dry ice
储存温度	?20ℂ�/td>
Gene Information	human ... ENC1(8507)

安全信息

储存分类代码	13 - Non Combustible Solids
WGK	WGK 1
闪点(F)	Not applicable
闪点(C)	Not applicable