Anti-PLSCR1 antibody produced in mouse

Anti-PLSCR1 antibody produced in mouse
MMTRA1B

产品介绍９�/div>

产品说明

一般描�?/p>

Phospholipid scramblase 1 (PLSCR1) is a 35kDa calcium dependant phospholipid translocator. The gene is located on human chromosome 3q24. The protein is overexpressed in tumor cells.

免疫厞�/p>

PLSCR1 (NP_066928.1, 1 a.a. ~ 318 a.a) full-length human protein.

Sequence
MDKQNSQMNASHPETNLPVGYPPQYPPTAFQGPPGYSGYPGPQVSYPPPPAGHSGPGPAGFPVPNQPVYNQPVYNQPVGAAGVPWMPAPQPPLNCPPGLEYLSQIDQILIHQQIELLEVLTGFETNNKYEIKNSFGQRVYFAAEDTDCCTRNCCGPSRPFTLRIIDNMGQEVITLERPLRCSSCCCPCCLQEIEIQAPPGVPIGYVIQTWHPCLPKFTIQNEKREDVLKISGPCVVCSCCGDVDFEIKSLDEQCVVGKISKHWTGILREAFTDADNFGIQFPLDLDVKMKAVMIGACFLIDFMFFESTGSQEQKSGVW

生化/生理作用

Phospholipid scramblase 1 (PLSCR1) bidirectionally transfers lipids across the membranes. It negatively regulates autophagy in mantle cell lymphoma (MCL). This protein is known to scramble phospholipids in the plasma membrane and thereby, disrupt membrane asymmetry. It functions as a multifunctional signalling molecule. It also has nuclease activity. PLSCR1 plays a role in cell proliferation, differentiation, apoptosis, pathogenesis of cancers, particularly leukemia.

外形

Solution in phosphate buffered saline, pH 7.4

基本信息

NACRES

NA.41

产品性质

质量水平	100
生物来源	mouse
偶联�?/td>	unconjugated
抗体形式	purified immunoglobulin
antibody product type	primary antibodies
克隆	polyclonal
形式	buffered aqueous solution
分子野�/td>	antigen ~35 kDa
species reactivity	human
technique(s)	western blot: 1 ��g/mL
NCBI登记叶�/td>	NM_021105.1
UniProt登记叶�/td>	O15162
运输	dry ice
储存温度	?20ℂ�/td>
Gene Information	human ... PLSCR1(5359)

安全信息

储存分类代码	13 - Non Combustible Solids
WGK	WGK 1
闪点(F)	Not applicable
闪点(C)	Not applicable