Anti-CTDSP1 (N-term) antibody produced in rabbit

Anti-CTDSP1 (N-term) antibody produced in rabbit
Anti-Nuclear LIM interactor-interacting factor 3
Anti-NLI-IF
Anti-NLI-interacting factor 3
Anti-Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1
Anti-NIF3, NLIIF

产品介绍９�/div>

产品说明

一般描�?/p>

CTDSP1 is a class 2C phosphatase with activity dependent on the conserved DxD motif. Expression of CTDSP1 inhibited activated transcription from several promoter-reporter gene constructs, but expression of a mutant lacking phosphatase activity enhanced transcription. Neuronal gene transcription is repressed in nonneuronal cells by the repressor element-1 (RE1)-silencing transcription factor/neuron-restrictive silencer factor (REST/NRSF; 600571) complex. REST/NRSF recruits SCPs to neuronal genes that contain RE1 elements, leading to neuronal gene silencing in nonneuronal cells. Phosphatase-inactive forms of SCP interfere with REST/NRSF function and promote neuronal differentiation of P19 stem cells. Likewise, small interfering RNA directed to the single Drosophila SCP unmasks neuronal gene expression in S2 cells. Thus, SCP activity is an evolutionarily conserved transcriptional regulator that acts globally to silence neuronal genes.

免疫厞�/p>

CTDSP1 (NP_067021, 11-41)
This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human CTDSP1.

外形

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.

基本信息

NACRES

NA.41

产品性质

生物来源	rabbit
质量水平	100
偶联�?/td>	unconjugated
抗体形式	IgG fraction of antiserum
antibody product type	primary antibodies
克隆	polyclonal
形式	buffered aqueous solution
species reactivity	human
technique(s)	immunohistochemistry: 1:50-1:100 indirect ELISA: 1:1000 western blot: 1:100-1:500
NCBI登记叶�/td>	NP_067021
UniProt登记叶�/td>	Q9GZU7
运输	dry ice
储存温度	?20ℂ�/td>
Gene Information	human ... CTDSP1(58190)

安全信息

储存分类代码	12 - Non Combustible Liquids
WGK	nwg
闪点(F)	Not applicable
闪点(C)	Not applicable