产品介绍９/div>
产品说明
一般描?/p>
The gene CTBP2 (C-terminal binding protein 2) encodes a member of the CtBP-family. The gene is mapped to human chromosome 21q21.3. It is found to be expressed ubiquitously, with higher expression in the heart, skeletal muscle, and pancreas.
免疫厞/p>
The antiserum was produced against synthesized peptide derived from human CtBP2.
Immunogen Range:396-445
生化/生理作用
The gene CTBP2 (C-terminal binding protein 2) encodes a protein that functions as a transcriptional co-repressor of several tumor suppressor genes resulting in enhanced cancer cell migration and invasion. Its expression is found to be upregulated in hepatocellular carcinoma (HCC). It may be a potential prognostic marker for post liver resection HCC. It is involved in several types of tumor initiation, progression and response to therapy. It is found to interact with the C-terminal region of adenovirus type 2/5 E1A protein, a region that negatively regulates tumorigenicity and the extent of oncogenic transformation.
特点和优劾/p>
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
外形
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
基本信息
产品性质
| 生物来源 |
rabbit |
| 质量水平 |
100 |
| 偶联?/td> |
unconjugated |
| 抗体形式 |
affinity isolated antibody |
| antibody product type |
primary antibodies |
| 克隆 |
polyclonal |
| 形式 |
buffered aqueous solution |
| 分子野/td> |
antigen 48 kDa |
| species reactivity |
mouse, rat, human |
| 浓度 |
~1 mg/mL |
| technique(s) |
ELISA: 1:1000
western blot: 1:500-1:1000 |
| NCBI登记叶/td> |
P56545 |
| UniProt登记叶/td> |
P56545 |
| 运输 |
wet ice |
| 储存温度 |
?20ℂ/td> |
| Gene Information |
human ... CTBP2(1488) |
安全信息
| 储存分类代码 |
12 - Non Combustible Liquids |
| WGK |
nwg |
| 闪点(F) |
Not applicable |
| 闪点(C) |
Not applicable |
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