产品名称９/div>
Monoclonal Anti-Interleukin-4 antibody produced in mouse
Anti-IL-4
产品介绍９/div>
产品说明
一般描?/p>
Interleukin-4 (IL-4) is a T cell derived chemokine that stimulates the Th2 mediated immune response and proliferation of B cells. The effects of IL-4 are mediated by two types of receptors, type I receptor consisting of IL-4R and common chain and type II receptor composed of IL-4R and IL-13R1. The signalling stimulated by IL-4 leads to activation of JAK/STAT6 and IRS-mediated PI3K/Akt pathway. Through these pathways, IL-4 is responsible for endocytic activity of macrophages, chemotaxis of leukocytes in response to inflammation, angiogenesis and regulation of nitric oxide metabolism in macrophages. Anti-tumor effects of IL-4 have been reported in cancers of breast, liver and renal cells
Anti-Interleukin-4 specifically recognizes human interleukin-4.
免疫厞/p>
purified,E. coli-derived recombinant human interleukin-4.
应用
Anti-Interleukin-4 antibody may be used for immunoblotting at a working concentration of 1-2 g/ml. For ELISA, a working concentration of 4 g/ml is recommended.
外形
Lyophilized from a 0.2 m filtered solution in phosphate buffered saline with 5% trehalose.
基本信息
| MDL编号 |
MFCD00212213 |
| NACRES |
NA.41 |
产品性质
| 质量水平 |
100 |
| 生物来源 |
mouse |
| 偶联?/td> |
unconjugated |
| 抗体形式 |
purified immunoglobulin |
| antibody product type |
primary antibodies |
| 克隆 |
3010, monoclonal |
| 形式 |
lyophilized powder |
| species reactivity |
human |
| technique(s) |
capture ELISA: suitable
western blot: 1-2 g/mL |
| 同位?亚型 |
IgG1 |
| UniProt登记叶/td> |
P05112 |
| 储存温度 |
?20ℂ/td> |
| Gene Information |
human ... IL4(3565) |
安全信息
| 储存分类代码 |
13 - Non Combustible Solids |
| WGK |
WGK 1 |
| 闪点(F) |
Not applicable |
| 闪点(C) |
Not applicable |
| 个人防护装备 |
Eyeshields, Gloves, type N95 (US) |
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