产品名称9/div>
ITK (352-end), active, GST tagged human
MGC126258
PSCTK2
LYK
EMT
MG C126257
产品介绍9/div>
产品说明
一般描?/p>
ITK (IL2-inducible T-cell kinase) is a member of the Tec family of tyrosine kinases. ITK is expressed in T-cells.
生化/生理作用
ITK (IL2-inducible T-cell kinase) is important for T-cell activation through the T-cell antigen receptor. Absence of ITK in T cells causes impairment in TCR (T cell receptor)-mediated actin polymerization, cell polarization and signaling events associated with cytoskeletal reorganization.
外形
Supplied in 50 mM Tris-HCl, pH 7.5, with 150 mM NaCl, 0.2 5mM DTT, 0.1 mM EGTA, 0.1 mM EDTA, 0.1 mM PMSF, and 25% glycerol.
法律信息
PRECISIO is a registered trademark of sigma-aldrich Co. LLC
基本信息
产品性质
| 质量水平 |
200 |
| 重组 |
expressed in baculovirus infectedSf9 cells |
| 产品纾/td> |
PRECISIO?Kinase |
| 测定 |
70% (SDS-PAGE) |
| 形式 |
buffered aqueous glycerol solution |
| specific activity |
49-67 nmol/minmg |
| 分子野/td> |
~53 kDa |
| UniProt登记叶/td> |
Q08881 |
| 运输 |
dry ice |
| 储存温度 |
?70ℂ/td> |
| Gene Information |
human ... ITK(3702) |
安全信息
| 储存分类代码 |
10 - Combustible liquids |
| WGK |
WGK 1 |
| 闪点(F) |
Not applicable |
| 闪点(C) |
Not applicable |
| 个人防护装备 |
Eyeshields, Gloves, multi-purpose combination respirator cartridge (US) |