产品介绍９/div>
产品说明
一般描?/p>
Human Isocitrate Dehydrogenase (IDH1), also known as oxalosuccinate decarboxylase, full length [amino acids 1-414 (end)] with C-terminal FLAG-tag, expressed in Sf9 cells via a baculovirus expression system.
应用
Human Isocitrate Dehydrogenase (IDH1) is useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling. It may be useful as a biomarker for diagnosis and prognosis prediction of non-small cell lung cancer .
生化/生理作用
Human Isocitrate Dehydrogenase (IDH1), also known as oxalosuccinate decarboxylase, is a full length amino acid with a C-terminal FLAG-tag and is expressed in Sf9 cells via a baculovirus expression system. IDH1 expression has been correlated with poor survival of non-small cell lung cancer. IDH1 promotes tumor growth .
外形
Solution in 45 mM Tris-HCl, 124 mM NaCl, 2.4 mM KCl, 90 g/ml FLAG peptide, 3 mM DTT, and 10% glycerol at pH 8.0.
基本信息
| 酶学委员?EC)编号 |
1.1.1.42 ( BRENDA | IUBMB ) |
| NACRES |
NA.54 |
产品性质
| 质量水平 |
200 |
| 重组 |
expressed inSf9 cells |
| 测定 |
0.30 mg/mL protein basis (Bradford)
90% (SDS-PAGE) |
| 形式 |
buffered aqueous glycerol solution |
| 分子野/td> |
47.6 kDa |
| NCBI登记叶/td> |
NM_005896 |
| 相关疾病 |
cancer (lung) |
| 运输 |
dry ice |
| 储存温度 |
?70ℂ/td> |
安全信息
| 储存分类代码 |
12 - Non Combustible Liquids |
| WGK |
WGK 1 |
| 闪点(F) |
Not applicable |
| 闪点(C) |
Not applicable |
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