Hemopexin from human plasma - �뵺�羺�ٷ��ַ

产品说明

一般描�?/p>

Hemopexin (HPX) is produced by cells of the central nervous system. It is a 60 kDa serum glycoprotein.

应用

Hemopexin from human plasma has been usedS. aureussurface colonization assay. It has also been used to stimulate mixed lymphocyte cells to determine the biomarkers in acute rejection.

包装

500 ��g in poly bottle

生化/生理作用

Hemopexin is an acute-phase protein that plays a major protective role against oxidative stress through its heme-scavenging activities. Hemopexin binds heme with high affinity and is critical for recycling the iron bound to heme molecules and for protecting against heme-induced cellular damage. Free heme, when released or lost from proteins like hemoglobin, can catalyze the formation of reactive oxygen species. Heme is lipophilic and interchelates into lipid membranes and participate in the formation of highly-toxic hydroxyl radicals. Hemopexin may also protect against the heme-mediated oxidation of LDL cholesterol.

Hemopexin may also serve an anti-inflammatory role via the negative regulation of IL-6 and TNF-�� secretion by activated macrophages.

外形

Lyophilized powder containing sodium phosphate, NaCl, and KCl, pH 7.4

产品性质

质量水平	100
生物来源	human plasma
测定	��95% (SDS-PAGE)
形式	lyophilized powder
分子野�/td>	~57 kDa
technique(s)	microbiological culture: suitable
NCBI登记叶�/td>	NP_000604
储存温度	?20ℂ�/td>
Gene Information	human ... HPX(3263)