Anti-c-Fos Antibody, clone 2G9C3 - �뵺�羺�ٷ��ַ

产品说明

一般描�?/p>

c-fos is a member of a family of immediate early gene (IEG) transcription factors (other members include Jun and Egr-1) also identified as proto-oncogenes. The basal expression of c-fos and other IEGs is typically low but increases relatively quickly and often dramatically (15-30 min for mRNA; 30-60 min for protein) in response to changes in cellular activity typically caused by external stimuli, such as stress or neuronal activation. Thus, these IEGs are being used to indicate specific activity driven cellular activation including the identification of neurons activated by various growth factors, neuroactive drugs, and correlated changes in behavioral or physiological states.

特异�?/p>

This antibody recognizes the ~55 kDa c-Fos and ~62 kDa v-Fos proteins.

免疫厞�/p>

Linear peptide corresponding to human c-Fos.

应用

Research Sub Category
Transcription Factors
Immunocytochemistry Analysis: A representative lot detected c-Fos in schwann cells. (Lafarga, M., et al. (2002). Molecular Biology of the Cell. 13:2771�C2782.)
Research Category
Epigenetics & Nuclear Function
Anti-c-Fos Antibody, clone 2G9C3 is a Mouse Monoclonal Antibody for detection of c-Fos also known as Proto-oncogene c-Fos, Cellular oncogene fos & has been validated in WB, ICC.

质量

Evaluated by Western Blot in HeLa cell lysate.

Western Blot Analysis: 0.5 ?g/mL of this antibody detected c-Fos on 10 ?g of HeLa cell lysate.

目标描述

~55/62 kDa observed. This antibody recognizes the ~55 kDa c-Fos and ~62 kDa v-Fos proteins. The calculated molecular wieght is 46 kDa; however, c-Fos has been observed at ~55 kDa in western blots. (Assim, M., et al. (2010). Journal of Biological Chemistry. 285(26):20343�C20357.)

外形

Format: Purified
Purified mouse monoclonal IgG1�� from cultured supernatant in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Protein G Purified

储存及稳定�?/p>

Stable for 1 year at 2-8��C from date of receipt.

分析说明

Control
HeLa cell lysate

其他说明

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

eCl@ss	32160702
NACRES	NA.41

产品性质

质量水平	100
生物来源	mouse
抗体形式	purified antibody
antibody product type	primary antibodies
克隆	2G9C3, monoclonal
species reactivity	human
technique(s)	immunocytochemistry: suitable western blot: suitable
同位�?亚型	IgG1��
NCBI登记叶�/td>	NP_005243
UniProt登记叶�/td>	P01100
运输	wet ice
Gene Information	human ... FOS(2353)