产品介绍9/div>
产品说明
一般描?/p>
Relatively selective blocker of L-type Ca2+channels. One of the most extensively studied blockers of 1,4-dihydropyridine-type Ca2+channels, and a pharmacologically-useful vasodilator. Induces apoptosis in human glioblastoma cells.
Relatively selective blocker of L-type Ca2+channels. One of the most extensively studied Ca2+channel blockers of 1,4-dihydropyridine-type and a pharmacologically useful vasodilator. Induces apoptosis in human glioblastoma cells.
包装
250 mg in Plastic ampoule
生化/生理作用
Product does not compete with ATP.
Reversible: no
Primary Target
L-type Ca2+ channels
Cell permeable: no
警告
Toxicity: Harmful & Carcinogenic / Teratogenic (E)
重悬
Following reconstitution, refrigerate (-20C). Stock solutions are stable for up to 3 months at -20C.
其他说明
Reid, K., et al. 1997.J. Pharmacol. Exp. Ther.283,993.
Kondo, S., et al. 1995.J. Neurosurg.82,469.
Antkiewicz-Michaluk, L., et al. 1994.Eur. J. Pharmacol.254,9.
Calabresi, P., et al. 1994.J. Neurosci.14,4871.
Akman, M.S., et al. 1993.Endocrinology132,1286.
Cirillo, M., et al. 1993.Circ. Res.72,847.
Young, R.J., et al. 1993.Biochim. Biophys. Acta1146,81.
Janis, R., et al. 1987.Adv. Drug Res.16,311.
法律信息
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
基本信息
| 经验(实验)分子弎/td> |
C17H18N2O6 |
| 分子野/td> |
346.33 |
| MDL编号 |
MFCD00057326 |
产品性质
| 质量水平 |
100 |
| 测定 |
98% (UV) |
| 形式 |
solid |
| manufacturer/tradename |
Calbiochem? |
| 储存条件 |
OK to freeze protect from light |
| 颜色 |
yellow |
| 溶解?/td> |
DMSO: soluble ethanol: soluble |
| 运输 |
ambient |
| 储存温度 |
10-30ℂ/td> |
| InChI |
1S/C17H18N2O6/c1-9-13(16(20)24-3)15(14(10(2)18-9)17(21)25-4)11-7-5-6-8-12(11)19(22)23/h5-8,15,18H,1-4H3 |
| InChI key |
HYIMSNHJOBLJNT-UHFFFAOYSA-N |
安全信息
| 象形国/td> |
 |
| 警示用语9/td> |
Warning |
| 危险声明 |
H302 |
| 预防措施声明 |
P264 - P270 - P301 + P312 - P501 |
| 危险分类 |
Acute Tox. 4 Oral |
| 储存分类代码 |
11 - Combustible Solids |
| WGK |
WGK 1 |
| 闪点(F) |
Not applicable |
| 闪点(C) |
Not applicable |