IL-36 GAMMA human

IL-36 GAMMA human
IL-1ε
IL-1F
IL-1H1

产品介绍９�/div>

产品说明

一般描�?/p>

IL-36�� is highly expressed in psoriatic plaques and in tissues containing epithelial cells. IL-36�� signals through the IL-1Rrp2 (IL-1R6) receptor, which is primarily expressed on certain dendritic cells. The interaction of the IL-1Rrp2 receptor with IL-36 ligands induces dendritic cell maturation and activation. IL-36�� also functions as an agonist of NF-kappaB, and can stimulate the inflammatory response in bronchial epithelial cells.

生化/生理作用

The IL-1 family is comprised of 11 structurally related ligands, including recently re-named IL-36 �� (IL-1F6), �� (IL-1F8) and �� (IL-1F9). Recombinant human IL-36�� is a 17.0 kDa protein containing 152 amino acid residues.

外形

Lyophilized from 10 mM Sodium Phosphate, pH 7.0 + 50 mM NaCl.

重悬

Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.1-1.0 mg/mL. Do not vortex. This solution can be stored at 2-8� for up to 1 week. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein (example 0.1% BSA) and store in working aliquots at -20� to -80�?

基本信息

NACRES

NA.32

产品性质

生物来源	human
重组	expressed inE. coli
测定	��95% (HPLC) ��95% (SDS-PAGE)
形式	lyophilized
分子野�/td>	17.0 kDa
包装	pkg of 10 ��g
杂质	<0.1 EU/��g endotoxin, tested
颜色	white to off-white
UniProt登记叶�/td>	Q9NZH7
运输	wet ice
储存温度	?20ℂ�/td>
Gene Information	human ... IL36B(27177)

安全信息

储存分类代码	12 - Non Combustible Liquids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable