产品介绍９/div>
产品说明
一般描?/p>
Special AT-rich sequence-binding protein 2 (SATB2) is a recently described marker that functions as a nuclear matrix-associated transcription factor. It has been reported that SATB2, in combination with CK20, could identify almost all colorectal carcinomas,1including poorly differentiated colorectal carcinomas.2Upper gastrointestinal (GI) carcinomas and pancreatic ductal carcinomas are usually negative for SATB2,1and ovarian carcinomas, lung adenocarcinomas, and adenocarcinomas from other origin are rarely positive for SATB2.1,2Therefore, SATB2 is a good marker for identifying a carcinoma of colorectal origin when working on a tumor of unknown primary.1,2,5Another potential utility of SATB2 is to identify neuroendocrine neoplasms/carcinomas of the left colon and rectum because SATB2 is usually negative in other neuroendocrine neoplasms of the GI tract, pancreas, and lung.3More recently, it has been shown in literature that SATB2 is a sensitive marker for tumors with osteoblastic differentiation.4
质量
联系
SATB2 Positive Control Slides, Product No. 384S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).
外形
Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide.
制备说明
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其他说明
For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com
法律信息
Cell Marque is a trademark of sigma-aldrich Co. LLC
基本信息
产品性质
| 生物来源 |
rabbit |
| 质量水平 |
500
100 |
| 偶联?/td> |
unconjugated |
| 抗体形式 |
culture supernatant |
| antibody product type |
primary antibodies |
| 克隆 |
EP281, monoclonal |
| 描述 |
(For In Vitro Diagnostic Use in Select Regions (See Chart)) |
| 形式 |
buffered aqueous solution |
| species reactivity |
human |
| 包装 |
vial of 0.1 mL concentrate (384R-14)
vial of 0.5 mL concentrate (384R-15)
bottle of 1.0 mL predilute (384R-17)
vial of 1.0 mL concentrate (384R-16)
bottle of 7.0 mL predilute (384R-18) |
| manufacturer/tradename |
Cell Marque? |
| technique(s) |
immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:25-1:100 |
| 同位?亚型 |
IgG |
| 控制 |
colon adenocarcinoma |
| 运输 |
wet ice |
| 储存温度 |
2-8ℂ/td> |
| 可视匕/td> |
nuclear |
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