产品介绍９/div>
产品说明
一般描?/p>
Mesothelin is a 40 kDa glycosyl-phosphatudylinositol-anchored glycoprotein cleaved from a 71kDa precursor protein encoded by the human mesothelin gene. Mesothelin is present on the surface of normal mesothelial cells.1Although the function of mesothelin is unknown, it is overexpressed in a wide variety of cancers including mesothelioma, pancreatic ductal adenocarcinoma, and ovarian carcinoma.1-6Mesothelin has proven to be a valuable marker for pancreatic ductal adenocarcinoma due to its strong reactivity in tumor tissue and absence in normal pancreas.1, 3-4Metastatic renal cell carcinoma can present clinical patterns that mimic primary mesothelioma, pancreatic ductal adenocarcinoma, and ovarian carcinoma.2, 4-6Mesothelin has demonstrated utility in the differential diagnosis between these primary tumors and corresponding metastatic renal cell carcinoma within the context of an antibody panel.4-6
质量
联系
Mesothelin Positive Control Slides, Product No. 439S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).
外形
Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide.
制备说明
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其他说明
For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com
法律信息
Cell Marque is a trademark of sigma-aldrich Co. LLC
基本信息
产品性质
| 生物来源 |
rabbit |
| 质量水平 |
500
100 |
| 偶联?/td> |
unconjugated |
| 抗体形式 |
culture supernatant |
| antibody product type |
primary antibodies |
| 克隆 |
EP140, monoclonal |
| 描述 |
(For In Vitro Diagnostic Use in Select Regions (See Chart)) |
| 形式 |
buffered aqueous solution |
| species reactivity |
human |
| 包装 |
bottle of 1.0 mL predilute (439R-17)
bottle of 7.0 mL predilute (439R-18)
vial of 0.1 mL concentrate (439R-14)
vial of 0.5 mL concentrate (439R-15)
vial of 1.0 mL concentrate (439R-16) |
| manufacturer/tradename |
Cell Marque? |
| technique(s) |
immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:25-1:100 |
| 同位?亚型 |
IgG |
| 运输 |
wet ice |
| 储存温度 |
2-8ℂ/td> |
安全信息
| 储存分类代码 |
12 - Non Combustible Liquids |
| WGK |
WGK 2 |
| 闪点(F) |
Not applicable |
| 闪点(C) |
Not applicable |
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