生物活?/h4>
Triciribine，也称为API-2，可抑制Akt的磷酸化水平和激酶活性
靶点信息
| HIV-1 (CEM-SS, H9, H9IIIB, U1 cells) |
Akt (PC3 cells) |
|
|
|
| 20 nM |
130 nM |
|
|
|
化学数据
| 目录叶/td> |
A13210 |
| 作用机制 |
Inhibitor (抑制? |
| M. Wt |
320.31 |
| Formula |
C13H16N6O4 |
| Purity |
>99% |
| Storage |
Store lyophilized at -20?C, keep desiccated.
In lyophilized form, the chemical is stable for36 months.
In solution, store at -20?C and use within3 monthsto prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles. |
| CAS No. |
35943-35-2 |
| Synonyms |
NSC 154020, TCN, API-2 |
| SMILES |
CN1C2=NC=NC3=C2C(=CN3[C@H]4[C@@H]([C@@H]([C@H](O4)CO)O)O)C(=N1)N |
储备液配刵/h4>
| Concentration / Solvent Volume / Mass |
1 mg |
5 mg |
10 mg |
| 0.1 mM |
31.22 mL |
156.1 mL |
312.2 mL |
| 0.5 mM |
6.24 mL |
31.22 mL |
62.44 mL |
| 1 mM |
3.12 mL |
15.61 mL |
31.22 mL |
| 5 mM |
0.62 mL |
3.12 mL |
6.24 mL |
*The above data is based on the productmolecular weight 320.31. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
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