生物活?/h4>
GENZ-644282是拓扑异构酶I的非喜树碱抑制剂，具有潜在的抗肿瘤活性
化学数据
| 目录叶/td> |
A13206 |
| 作用机制 |
Inhibitor (抑制? |
| M. Wt |
407.42 |
| Formula |
C22H21N3O5 |
| Purity |
>99% |
| Storage |
Store lyophilized at -20?C, keep desiccated.
In lyophilized form, the chemical is stable for36 months.
In solution, store at -20?C and use within3 monthsto prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles. |
| CAS No. |
529488-28-6 |
| Synonyms |
GENZ644282; GENZ 644282 |
| SMILES |
CNCCN1C2=C(C=NC3=CC4=C(C=C32)OCO4)C5=CC(=C(C=C5C1=O)OC)OC |
溶解?/h4>
| In vitro |
DMSO |
Insoluble |
| Water |
Insoluble |
| Ethanol |
Insoluble |
*<1 mg/ml means slightly soluble or insoluble.
*Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
储备液配刵/h4>
| Concentration / Solvent Volume / Mass |
1 mg |
5 mg |
10 mg |
| 0.1 mM |
24.54 mL |
122.72 mL |
245.45 mL |
| 0.5 mM |
4.91 mL |
24.54 mL |
49.09 mL |
| 1 mM |
2.45 mL |
12.27 mL |
24.54 mL |
| 5 mM |
0.49 mL |
2.45 mL |
4.91 mL |
*The above data is based on the productmolecular weight 407.42. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
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