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Z-VAD-FMK
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验、/div>
Z-VAD-FMK图片
CAS NO: 187389-52-2
规格: ?8%
包装与价格：
包装 价格(?
1mg 电议
2mg 电议
5mg 电议
10mg 电议
25mg 电议
50mg 电议
100mg 电议
250mg 电议
500mg 电议

产品介绍
理化性质和储存条仵/div>
Molecular Weight (MW) 467.49
Formula C22H30FN3O7
CAS No. 187389-52-2
Storage -20 for 3 years in powder form
-80 for 2 years in solvent
Solubility(In vitro) DMSO: 93 mg/mL (198 mM)
Water:<1 mg/mL (slightly soluble or insoluble)
Ethanol: 24 mg/mL warming (51 mM)
Other info

Synonym: Z-VAD-FMK; Z-VAD(OMe)-FMK; Z-Val-Ala-Asp(OMe)-FMK; Z VADFMK; ZVADFMK.

Chemical Name: methyl (3S)-5-fluoro-3-[[(2S)-2-[[(2S)-3-methyl-2-(phenylmethoxycarbonylamino)butanoyl]amino]propanoyl]amino]-4-oxopentanoate

SMILES Code: O=C(OC)C[C@H](NC([C@@H](NC([C@@H](NC(OCC1=CC=CC=C1)=O)C(C)C)=O)C)=O)C(CF)=O
实验参考方泔/div>
In Vitro Z-VAD-FMK (10 mM) inhibits apoptosis in THP.1 cells. Z-VAD-FMK (10 μM) inhibits activation of PARP protease activity in control THP.1 cell lysates.
In Vivo The right ear swelling degree, weight differences and thickness between two ears in the 1.25 mML Z-VAD-FMK group were significantly lower than those of the negative control (NC). The levels of INF-γ and IL-2 in the ear skin lesions, the mean intensity of BrdU in T lymphocytes, and the percent of activation markers-positive T lymphocytes were all lower than those of NC.
Animal model C57BL mice
Formulation & Dosage 1.25 mMl; Ear provocation
References Zhonghua Yi Xue Za Zhi. 2012 Jul 24;92(28):1992-6.
生物活?/div>




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