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NSC 319726
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验、/div>
NSC 319726图片
CAS NO: 71555-25-4
规格: ?8%
包装与价格：
包装 价格(?
5mg 电议
10mg 电议
25mg 电议
50mg 电议
100mg 电议
250mg 电议
500mg 电议

产品介绍
理化性质和储存条仵/div>
Molecular Weight (MW) 234.32
Formula C11H14N4S
CAS No. 71555-25-4
Storage -20 for 3 years in powder form
-80 for 2 years in solvent
Solubility(In vitro) DMSO: 19 mg/mL (81.08 mM)
Water:<1 mg/mL (slightly soluble or insoluble)
Ethanol: <1 mg/mL
Synonyms NSC319726; NSC-319726; NSC 319726
实验参考方泔/div>
General NSC319726 (5mg/kg, 7days) exhibits greater toxicity for p53(R172H/R172H) mice, with only 30% survival, as compared to 100% survival for p53+/+ and p53-/- mice. NSC319726 inhibits the growth of TOV112D-p53(R175H) xenografts, but not H460 (p53+/+) and MDAMB468-p53(R273W) xenografts.
Animal model p53+/+, p53-/- and p53R172H knockin mice
Formulation DMSO
Dosages 5-10 mg/kg/day, up to 7 days
Administration i.p.
References [1] Yu X, et al. Cancer Cell, 2012, 21(5), 614-625.
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