生物活?/h4>
IQ-1S是一种选择性JNK3抑制剂，对于JNK1??的IC50值分别为390?60?7 nM
化学数据
| 目录叶/td> |
A16062 |
| 作用机制 |
Inhibitor (抑制? |
| M. Wt |
247.25 |
| Formula |
C15H9N3O |
| Purity |
>99% |
| Storage |
Store lyophilized at -20?C, keep desiccated.
In lyophilized form, the chemical is stable for36 months.
In solution, store at -20?C and use within3 monthsto prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles. |
| CAS No. |
23146-22-7 |
| Synonyms |
IQ1S |
| SMILES |
O/N=C1C2=C(C3=NC4=CC=CC=C4N=C3\1)C=CC=C2 |
溶解?/h4>
| In vitro |
DMSO |
45 mg/mL (181.99 mM) |
| Water |
Insoluble |
| Ethanol |
1 mg/mL (4.04 mM) |
*<1 mg/ml means slightly soluble or insoluble.
*Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
储备液配刵/h4>
| Concentration / Solvent Volume / Mass |
1 mg |
5 mg |
10 mg |
| 0.1 mM |
40.44 mL |
202.22 mL |
404.45 mL |
| 0.5 mM |
8.09 mL |
40.44 mL |
80.89 mL |
| 1 mM |
4.04 mL |
20.22 mL |
40.44 mL |
| 5 mM |
0.81 mL |
4.04 mL |
8.09 mL |
*The above data is based on the productmolecular weight 247.25. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
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