生物活?/h4>
L67是DNA连接酶抑制剂。L67抑制DNA连接酶I和III。L67是关于刻痕DNA的简单竞争性抑制剂
化学数据
| 目录叶/td> |
A15978 |
| 作用机制 |
Inhibitor (抑制? |
| M. Wt |
486.12 |
| Formula |
C16H14Br2N4O4 |
| Purity |
>99% |
| Storage |
Store lyophilized at -20?C, keep desiccated. In lyophilized form, the chemical is stable for36 months. In solution, store at -20?C and use within3 monthsto prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles. |
| CAS No. |
325970-71-6 |
| Synonyms |
L-67, L 67 |
| SMILES |
O=C(N/N=C/C1=CC([N+]([O-])=O)=CC=C1O)CNC2=CC(Br)=C(C)C(Br)=C2 |
储备液配刵/h4>
| Concentration / Solvent Volume / Mass |
1 mg |
5 mg |
10 mg |
| 0.1 mM |
20.57 mL |
102.86 mL |
205.71 mL |
| 0.5 mM |
4.11 mL |
20.57 mL |
41.14 mL |
| 1 mM |
2.06 mL |
10.29 mL |
20.57 mL |
| 5 mM |
0.41 mL |
2.06 mL |
4.11 mL |
*The above data is based on the productmolecular weight 486.12. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.