(20R)-ginsenoside Rg3 ((20R)-Propanaxadiol) 是人参根中的一种活性化合物,可抑制血管内皮生长因 (VEGF) (IC50\u003d10 nM) 和抗肿瘤活性、div>
| Cas No. |
38243-03-7 |
| 别名 |
(20R)-人参皂苷Rg3; (20R)-Propanaxadiol; R-ginsenoside Rg3 |
| 化学同/td> |
2-[4,5-dihydroxy-2-[[12-hydroxy-17-(2-hydroxy-6-methylhept-5-en-2-yl)-4,4,10,13,14-pentamethyl-2,3,5,6,7,8,9,11,12,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl]oxy]-6-(hydroxymethyl)oxan-3-yl]oxy-6-(hydroxymethyl)oxane-3,4,5-triol |
| Canonical SMILES |
CC(=CCCC(C)(C1CCC2(C1(C(CC3C2CCC4C3(CCC(C4(C)C)OC5C(C(C(C(O5)CO)O)O)OC6C(C(C(C(O6)CO)O)O)O)C)O)C)C)O)C |
| 分子弎/td> |
C42H72O13 |
| 分子野/td> |
785.01 |
| 溶解?/td> |
Ethanol: slightly soluble |
| General tips |
For obtaining a higher solubility , please warm the tube at 37 and shake it in the ultrasonic bath for a while. |
| Shipping Condition |
Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
| 产品描述 |
20(R)-ginsenoside Rg3 (20(R)-Propanaxadiol), one of the active compounds present in ginseng root, has a potent angiosuppressive and antitumor activities[1][2]. References: [1]. Liu L, et al. Enzymatic preparation of 20(S, R)-protopanaxadiol by transformation of 20(S, R)-Rg3 from blackginseng. Phytochemistry. 2010 Sep;71(13):1514-20. [2]. Yue PY, et al. The angiosuppressive effects of 20(R)- ginsenoside Rg3. Biochem Pharmacol. 2006 Aug 14;72(4):437-45. |