M-110 is a novel and potent inhibitor of protein arginine N-methyltransferases (PRMTs) with anticancer activity. It is also an isoform-selective, cell permeable and potent ATP-competitive inhibitor of the PIM kinase family that prefers PIM-3. IT inhibits the proliferation of prostate cancer cell lines with IC50s between 0.6 to 0.9 μM, with no activity on normal human peripheral blood mononuclear cells up to 40 μM.