生物活?/h4>
Eliglustat是葡萄糖神经酰胺合成酶的一种特异而有效的抑制剂
靶点信息
| glucosylceramide synthase |
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化学数据
| 目录叶/td> |
A12386 |
| 作用机制 |
Inhibitor (抑制? |
| M. Wt |
404.54 |
| Formula |
C23H36N2O4 |
| Purity |
>99% |
| Storage |
Store lyophilized at -20?C, keep desiccated.
In lyophilized form, the chemical is stable for36 months.
In solution, store at -20?C and use within3 monthsto prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles. |
| CAS No. |
491833-29-5 |
| Synonyms |
Genz-99067, Genz99067, Genz 99067 |
| SMILES |
CCCCCCCC(N[C@H](CN1CCCC1)[C@@H](C2=CC=C3OCCOC3=C2)O)=O |
溶解?/h4>
| In vitro |
DMSO |
77 mg/mL (190.33 mM) |
| Water |
Insoluble |
| Ethanol |
77 mg/mL |
*<1 mg/ml means slightly soluble or insoluble.
*Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
储备液配刵/h4>
| Concentration / Solvent Volume / Mass |
1 mg |
5 mg |
10 mg |
| 0.1 mM |
24.72 mL |
123.6 mL |
247.19 mL |
| 0.5 mM |
4.94 mL |
24.72 mL |
49.44 mL |
| 1 mM |
2.47 mL |
12.36 mL |
24.72 mL |
| 5 mM |
0.49 mL |
2.47 mL |
4.94 mL |
*The above data is based on the productmolecular weight 404.54. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
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