SB357134 is a potent, selective and orally bioavailable 5-HT6 receptor antagonist. SB-357134 and other 5-HT6 antagonists show nootropic effects in animal studies, and have been proposed as potential novel treatments for cognitive disorders such as schizophrenia and Alzheimer's disease. References: Meneses A. Do serotonin(1-7) receptors modulate short and long-term memory? Neurobiol Learn Mem. 2007 May;87(4):561-72. Epub 2007 Jan 16. PubMed PMID: 17224282.

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CAS�?19963-52-7