生物活?/h4>
BMS-794833是Met和VEGFR-2的有效ATP竞争性抑制剂，IC50?.7?5 nM
靶点信息
化学数据
| 目录叶/td> |
A10154 |
| 作用机制 |
Inhibitor (抑制? |
| M. Wt |
468.8 |
| Formula |
C23H15ClF2N4O3 |
| Purity |
>99% |
| Storage |
Store lyophilized at -20?C, keep desiccated.
In lyophilized form, the chemical is stable for36 months.
In solution, store at -20?C and use within3 monthsto prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles. |
| CAS No. |
1174046-72-0 |
| Synonyms |
BMS794833 |
| SMILES |
C1=CC(=CC=C1C2=CNC=C(C2=O)C(=O)NC3=CC(=C(C=C3)OC4=C(C(=NC=C4)N)Cl)F)F |
溶解?/h4>
| In vitro |
DMSO |
85 mg/mL (181.29 mM) |
| Water |
Insoluble |
| Ethanol |
Insoluble |
*<1 mg/ml means slightly soluble or insoluble.
*Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
储备液配刵/h4>
| Concentration / Solvent Volume / Mass |
1 mg |
5 mg |
10 mg |
| 0.1 mM |
21.33 mL |
106.66 mL |
213.31 mL |
| 0.5 mM |
4.27 mL |
21.33 mL |
42.66 mL |
| 1 mM |
2.13 mL |
10.67 mL |
21.33 mL |
| 5 mM |
0.43 mL |
2.13 mL |
4.27 mL |
*The above data is based on the productmolecular weight 468.8 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
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