生物活�?/h4>

P276-00是一种新型CDK1，CDK4和CDK9抑制剂，IC50分别�?9 nM�?3 nM�?0 nM。在�?/3阶段�

Targets

化学数据

溶解�?/h4>

In vitro (25°C)	DMSO	79 mg/mL (180.24 mM)
	Water	79 mg/mL (180.24 mM)
	Ethanol	6 mg/mL (13.69 mM)
In vivo	30% propylene glycol, 5% Tween 80, 65% D5W	28 mg/mL
*<1 mg/ml means slightly soluble or insoluble. *Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

储备液配刵�/h4>

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	22.82 mL	114.08 mL	228.15 mL
0.5 mM	4.56 mL	22.82 mL	45.63 mL
1 mM	2.28 mL	11.41 mL	22.82 mL
5 mM	0.46 mL	2.28 mL	4.56 mL

*The above data is based on the productmolecular weight 438.3. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.