DREADD agonist 21 diHCl is a highly potent human muscarinic acetylcholine M3 receptors (hM3Dq) agonist (EC50=1.7 nM). References: [1]. Chen X, et al. The first structure-activity relationship studies for designer receptors exclusively activated by designer drugs. ACS Chem Neurosci. 2015 Mar 18;6(3):476-84. [2]. Thompson KJ, et al. DREADD Agonist 21 Is an Effective Agonist for Muscarinic-Based DREADDs in Vitro and in Vivo. ACS Pharmacol Transl Sci. 2018 Sep 14;1(1):61-72.

纯度：≥98%