生物活?/h4>
Anidulafungin是一种半合成的环脂肽，属于棘白菌素类，于1995年报道，由礼来公司开发。Anidulafungin抑制β-?,3?D-葡聚糖的合成，??,3?D-葡聚糖是敏感真菌细胞壁的一个重要组成部分，在文献中被广泛引用，引用超过400篇
靶点信息
化学数据
| 目录叶/td> |
A13436 |
| 作用机制 |
Inhibitor (抑制? |
| M. Wt |
1140.25 |
| Formula |
C58H73N7O17 |
| Purity |
>99% |
| Storage |
Store lyophilized at -20?C, keep desiccated.
In lyophilized form, the chemical is stable for36 months.
In solution, store at -20?C and use within3 monthsto prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles. |
| CAS No. |
166663-25-8 |
| SMILES |
CCCCCOC1=CC=C(C=C1)C2=CC=C(C=C2)C3=CC=C(C=C3)C(=O)N[C@H]4C[C@H]([C@H](NC(=O)[C@@H]5[C@H]([C@H](CN5C(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H]6C[C@H](CN6C(=O)[C@@H](NC4=O)[C@@H](C)O)O)[C@@H]([C@H](C7=CC=C(C=C7)O)O)O)[C@@H](C)O)C)O)O)O |
溶解?/h4>
| In vitro |
DMSO |
Warmed: 88 mg/mL (77.18 mM) |
| Water |
Insoluble |
| Ethanol |
Insoluble |
*<1 mg/ml means slightly soluble or insoluble.
*Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
储备液配刵/h4>
| Concentration / Solvent Volume / Mass |
1 mg |
5 mg |
10 mg |
| 0.1 mM |
8.77 mL |
43.85 mL |
87.7 mL |
| 0.5 mM |
1.75 mL |
8.77 mL |
17.54 mL |
| 1 mM |
0.88 mL |
4.39 mL |
8.77 mL |
| 5 mM |
0.18 mL |
0.88 mL |
1.75 mL |
*The above data is based on the productmolecular weight 1140.25. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
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