生物活?/h4>
CHC是单羧酸转运（MCT）抑制剂。在神经胶质瘤中具有抗肿瘤和抗血管生成活性；降低U251细胞的糖酵解代谢，迁移和侵袭
化学数据
| 目录叶/td> |
A13372 |
| 作用机制 |
Inhibitor (抑制? |
| M. Wt |
189.17 |
| Formula |
C10H7NO3 |
| Purity |
>99% |
| Storage |
Store lyophilized at -20?C, keep desiccated.
In lyophilized form, the chemical is stable for36 months.
In solution, store at -20?C and use within3 monthsto prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles. |
| CAS No. |
28166-41-8 |
| Synonyms |
-Cyano-4-hydroxycinnamic acid |
| SMILES |
C1=CC(=CC=C1/C=C(\C#N)/C(=O)O)O |
溶解?/h4>
| In vitro |
DMSO |
32 mg/mL (169.16 mM) |
| Water |
Insoluble |
| Ethanol |
7 mg/mL (37 mM) |
*<1 mg/ml means slightly soluble or insoluble.
*Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
储备液配刵/h4>
| Concentration / Solvent Volume / Mass |
1 mg |
5 mg |
10 mg |
| 0.1 mM |
52.86 mL |
264.31 mL |
528.63 mL |
| 0.5 mM |
10.57 mL |
52.86 mL |
105.73 mL |
| 1 mM |
5.29 mL |
26.43 mL |
52.86 mL |
| 5 mM |
1.06 mL |
5.29 mL |
10.57 mL |
*The above data is based on the productmolecular weight 189.17. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
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