Fmoc-NH-PEG1-CH2COOH是一种可降解的ADClinker,用于抗体药物偶联物(ADC)合成。
| Cas No. |
260367-12-2 |
| 别名 |
FMOC-5-氨基-3-氧戊酸 |
| Canonical SMILES |
O=C(O)COCCNC(OCC1C2=C(C3=C1C=CC=C3)C=CC=C2)=O |
| 分子式 |
C19H19NO5 |
| 分子量 |
341.36 |
| 储存条件 |
Store at -20℃ |
| General tips |
For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition |
Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
| 半岛bd体育手机客户端 描述 |
Fmoc-NH-PEG1-CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker. [1]. Lorenzo Benatuil, et al. Anti-cd98 antibodies and antibody drug conjugates. WO2017214456A. |