生物活?/h4>
BAY 57-1293是一种有效的解旋酶引发酶抑制剂。BAY 57-1293通过废除病毒引发?解旋酶复合物的酶促活性,在体外的纳摩尔范围内抑制1型和2型单纯疱疹病毒(HSV)的复制
靶点信息
化学数据
| 目录叶/td> |
A13324 |
| 作用机制 |
Inhibitor (抑制? |
| M. Wt |
402.49 |
| Formula |
C18H18N4O3S2 |
| Purity |
>99% |
| Storage |
Store lyophilized at -20?C, keep desiccated. In lyophilized form, the chemical is stable for36 months. In solution, store at -20?C and use within3 monthsto prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles. |
| CAS No. |
348086-71-5 |
| Synonyms |
BAY-57-1293; BAY57-1293; BAY 57-1293 |
| SMILES |
CC1=C(SC(=N1)N(C)C(=O)CC2=CC=C(C=C2)C3=CC=CC=N3)S(=O)(=O)N |
溶解?/h4>
| In vitro |
DMSO |
74 mg/mL (183.85 mM) |
| Water |
Insoluble |
| Ethanol |
Insoluble |
*<1 mg/ml means slightly soluble or insoluble. *Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
储备液配刵/h4>
| Concentration / Solvent Volume / Mass |
1 mg |
5 mg |
10 mg |
| 0.1 mM |
24.85 mL |
124.23 mL |
248.45 mL |
| 0.5 mM |
4.97 mL |
24.85 mL |
49.69 mL |
| 1 mM |
2.48 mL |
12.42 mL |
24.85 mL |
| 5 mM |
0.5 mL |
2.48 mL |
4.97 mL |
*The above data is based on the productmolecular weight 402.49. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.