生物活?/h4>
GSK 650394是一种糖皮质激素和血清调节激?（SGK1）抑制剂，对LNCaP前列腺癌细胞系表现出抗增殖特性
靶点信息
化学数据
| 目录叶/td> |
A13309 |
| 作用机制 |
Inhibitor (抑制? |
| M. Wt |
382.45 |
| Formula |
C25H22N2O2 |
| Purity |
>99% |
| Storage |
Store lyophilized at -20?C, keep desiccated.
In lyophilized form, the chemical is stable for36 months.
In solution, store at -20?C and use within3 monthsto prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles. |
| CAS No. |
890842-28-1 |
| Synonyms |
GSK 650394, GSK650394 |
| SMILES |
C1CCC(C1)C2=C(C=CC(=C2)C3=CNC4=NC=C(C=C34)C5=CC=CC=C5)C(=O)O |
溶解?/h4>
| In vitro |
DMSO |
72 mg/mL (188.25 mM) |
| Water |
Insoluble |
| Ethanol |
Insoluble |
*<1 mg/ml means slightly soluble or insoluble.
*Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
储备液配刵/h4>
| Concentration / Solvent Volume / Mass |
1 mg |
5 mg |
10 mg |
| 0.1 mM |
26.15 mL |
130.74 mL |
261.47 mL |
| 0.5 mM |
5.23 mL |
26.15 mL |
52.29 mL |
| 1 mM |
2.61 mL |
13.07 mL |
26.15 mL |
| 5 mM |
0.52 mL |
2.61 mL |
5.23 mL |
*The above data is based on the productmolecular weight 382.45. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
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