Pedaliin 6''-acetate (compound 10) 是一种可从甘青青兰中分离出的天然产物。Pedaliin 6''-acetate 显示出抗氧化活性并对阿霉素 (DOX) 诱导 H9c2 心肌细胞毒性具有细胞保护作用,
EC50值为 19.1 μM、/div>
| 生物活?/td> |
Pedaliin 6''-acetate (compound 10) is a natural product that can be isolated fromDracocephalum tanguticum. Pedaliin 6''-acetate shows antioxidative activity and cytoprotective effect on doxorubicin (DOX)-induced toxicity in H9c2 cardiomyocytes with anEC50value of 19.1 μM[1].
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体外研究 (In Vitro) |
Pedaliin 6''-acetate scavenges 1,1-diphenyl-2-picrylhydrazyl (DPPH) free radical with an EC50value of 95.24 μM[1]. Pedaliin 6''-acetate chelates ferrous ions with an EC50value of 1.13 mM[1]. Pedaliin 6''-acetate scavenges ABTS+cation radical with an EC50value of 76.19 μM[1]. Pedaliin 6''-acetate shows cytoprotective effect on DOX-induced toxicity in H9c2 cardiomyocytes with an EC50value of 19.1μM[1].
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| Formula |
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| 结构分类 |
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| 来源 |
- Plants
- Labiatae
- Dracocephalum tanguticumMaxim.
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| 运输条件 |
Room temperature in continental US; may vary elsewhere.
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| 储存方式 |
Please store the product under the recommended conditions in the Certificate of Analysis.
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