Fumagillin (NSC9168) 是一种抗菌化合物，于 1949 年首次从真菌 Aspergillus fumigatu 中分离出来、div>
| Cas No. |
23110-15-8 |
| 别名 |
烟曲霉素; Amebacilin; NSC9168 |
| 化学同/td> |
10-[[5-methoxy-4-[2-methyl-3-(3-methylbut-2-enyl)oxiran-2-yl]-1-oxaspiro[2.5]octan-6-yl]oxy]-10-oxodeca-2,4,6,8-tetraenoic acid |
| Canonical SMILES |
CC(=CCC1C(O1)(C)C2C(C(CCC23CO3)OC(=O)C=CC=CC=CC=CC(=O)O)OC)C |
| 分子弎/td> |
C26H34O7 |
| 分子野/td> |
458.55 |
| 溶解?/td> |
81.3mg/mL in DMSO, 2.58 mg/mL in EtOH with ultrasonic |
| 储存条件 |
Store at -20ℂ/td> |
| General tips |
For obtaining a higher solubility , please warm the tube at 37 and shake it in the ultrasonic bath for a while. |
| Shipping Condition |
Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 |
Fumagillin(NSC9168) is a complex biomolecule and used as an antimicrobial agent.Target: AntiparasiticFumagillin is an active amebicide and anti-infective isolated from the fungus Aspergillus fumigatus. Fumagillin does exhibit some side effects that have deterred its acceptance as a viable treatment, but the current body of research on the synthesis of novel analogs of this molecule shows an exciting and promising revival of this drug as both an anti-infective and antiangiogenic agent [1]. References:
[1]. Lefkove, B., B. Govindarajan, and J.L. Arbiser, Fumagillin: an anti-infective as a parent molecule for novel angiogenesis inhibitors. Expert Rev Anti Infect Ther, 2007. 5(4): p. 573-9. |
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