BACE1-IN-2 is a 1,4-Oxazine β-Secretase 1 (BACE1) inhibitor with anIC₅₀of 22 nM^[1].

BACE1-IN-2 (Compound 3) is 10-fold more potent toward BACE1 than BACE2, inhibition of which may lead to hair depigmentation. BACE1-IN-2 inhibits hAβ42 cell with an IC₅₀of 6.0 nM^[1].

421.35

C₁₉H₁₅F₄N₅O₂

1352416-78-4

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.